Study of Liver Abscess: Its Etiology and Treatment in Telangana Population

  • T V Ramanachary Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India
  • Khaja Abdul Muqeet Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India
Keywords: Abscess, Percutaneous needle aspiration, Percutaneous catheter drainage

Abstract

Introduction: Liver (hepar) is a largest metabolic center in the body. It is said that the liver is the busiest port in the lake of life. Etiology of the liver abscess has changed to pyogenic abscess (PA). PA of liver remains a major diagnostic and therapeutic challenge despite advances in diagnostic technology and new strategies for treatment. Materials and Methods: Ninety-six patients aged between 25 and 65 years visiting MediCiti Hospital (MediCiti Institute of Medical Sciences), Ghanpur, Medchal – 501401, Telangana, were selected for study. Results: The clinical manifestation was as follows: 72 (75%) had fever, 72 (75%) had abdominal pain, 70 (72.9%) had nausea and vomiting, 48 (50%) had night sweats, 42 (43.7%) had weight loss, 9 (9.37%) had jaundice, 29 (302%) had diarrhea, and 38 (39.5%) had chest symptoms (cough, chest pain, and shortness of breath). Hematological and biological study had 54 (56.2%) 45–46 (u/I) alanine aminotransferase (ALT), 42 (43.7%) had 47–48 ALT, and 38 (39.5%) had 40–41 (u/I) ALT; 38 (39.5%) had 40–41 aspirate aminotransferase (AST) and 58 (60.4%) had 42–43 (u/I) AST; 62 (64.5%) had 470–471 alkaline phosphatase (ALP) (u/I) and 34 (35.4%) had 472–473 ALP (U/I); 52 (54.1%) had 11–12 serum bilirubin (Mm/I) and 44 (45.8%) had 13–14 serum bilirubin (Mm/I); 62 (64.5%) had 11–11.5 hemoglobin (Hb)% (gm/I), 62 (64.5%) had 11.6–11.7 Hb% (gm/I), and 34 (35.4%) had 11.6–11.7 Hb% (gm/I); 51 (53.%) had 17.2–17.3 white blood count (WBC) (× 109/I) and 45 (46.8%) had 17.4–17.5 WBC (× 109/I); and 53 (55.2%) had 14.45–14.46 neutrophils and 43 (44.7%) had neutrophils 14.47–14.48 (109/I). The isolated bacteria were as follows: 32 (33.3%) were Gram negative, 17 (17.7%) were anaerobic Bacilli, and 47 (48.9%) were streptococci. Conclusion: The initial diagnostic investigation, antibiotics as first-line treatment followed by antibiotic with PNA/PDA, and ultimately, surgery was effective treatment. Such types of approach will have better prognosis except in patients with malignant disease 

Author Biographies

T V Ramanachary, Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India

Associate Professor, Department of General Surgery,

Khaja Abdul Muqeet, Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India

Assistant Professor, Department of General Surgery,

Published
2019-05-30
Section
Articles