Study of Hypertensive Disorders in Pregnancy and Its Outcome in Neonates

  • Vasavi Korupolu A Amrin Nimra Institute of Medical Sciences, Vijayawada, Andhra Pradesh, India.
Keywords: Eclampsia, Intrauterine growth restriction, Low birth weight, Lower segment cesarean section, Preeclampsia

Abstract

Background: A hypertensive (HTN) disorder of pregnancy is a multi-factorial disorder and seriously endangers the safety of fetus during pregnancy.
Methods: 150 HTN pregnant women were selected for study and followed them till delivery and 6–8 weeks post-delivery, routine Blood examination, complete blood count, CT, BT, and serum electrolyte ultrasound (USG) was done. Fetal monitoring included DFMC, FHR, NST umbilical, and cerebral Doppler, USG to assess the fetal serial growth, AFI, BPP, placental location, and maturity.
Results: Types of delivery – 97 (64.6%) lower segment cesarean section, 39 (26%) normal vaginal delivery, 5 (3.3%) forceps, 9 (6%) consanguinity, 30 (20%) had <140 systolic, 90 diastolic blood pressure (BP), 80 (53.3%) had 140–159 systolic, 90–190 diastolic BP, 40 (26.6%) had >160 systolic, and >110 diastolic BP. The gestational ages of neonates were – 21 (14%) were <32 weeks, 40 (26.6%) were 32–36 weeks, and 89 (59.3%) were 37–42 weeks. Birth weight of neonates 70 (46.6%) had low birth weight (LBW), 17 (11.3%) had very LBW, 33 (22%) had normal weight, 30 (20%) had intrauterine growth restriction, 118 (78.6%) were alive, and 32 (21.3%) neonatal deaths were noted.
Conclusion: Eclampsia is still common and serious complications of pregnancy. Proper antenatal care, detection of preeclampsia with early management and timely referral of high risk patients would reduce of the maternal and perinatal morbidity and mortality.

Author Biography

Vasavi Korupolu A Amrin, Nimra Institute of Medical Sciences, Vijayawada, Andhra Pradesh, India.

Assistant Professor, Department of Obstetrics and Gynaecology.

References

1. Shah A, Fawole B. Cesarean delivery outcomes from the
WHO global survey on maternal and perinatal health in
Africa. Int J Gynaecol Obstetr 2009;107:191-7.
2. Mcclure EM, Saleem S, Pasha O, Goldenberg RL. Stillbirth
in developing countries: A review of causes, risk factors
and prevention strategies. J Matern Fetal Neonatal Med
2009;22:189-90.
3. Hutter D, Kingdom J, Jaeggi E. Causes and mechanisms of
intrauterine hypoxia and its impact on the fetal cardiovascular
system: A review. Int J Pediatr 2010;2010:401323.
4. Bhide A, Kumaran SA. Hyper tension disorders in pregnancy.
In: Arias’ Practical Guide to High-Risk Pregnancy and
Delivery: A South Asian Perspective. 4th ed., Ch. 13.
Haryana, India: Elsevier; 2015. p. 185-232.
5. Sibai BM. Antihypertensive drugs during pregnancy. Semin
Perinatol 2001;25:159-65.
6. Roberts CL, Algert CS, Morris JM, Ford JB, Henderson-
Smart DJ. Hypertensive disorders in pregnancy:
A population-based study. Med J Aust 2005;182:332-5.
7. Yadav S, Saxena U, Yadav R, Gupta S. Hypertensive
disorders of pregnancy and maternal and foetal outcome:
A case controlled study. J Indian Med Assoc 1997;95:848-5.
8. Chesely LC. History. In: Chesley LC, editor. Hypertensive
Disorders in Pregnancy. New York, Appleton: Century
Crofts; 1978. p. 17034.
9. Lyall F, Greer IA. The vascular endothelium in normal
pregnancy and pre-eclampsia. Rev Reprod 1996;1:107-16.
10. Shaflas AF, Olson DR. Epidemiology of preeclampsia and
eclampsia in the United States, 1979-1986. Am J Obstet
Gynecol 1990;163:460-5.
11. Aucott SW, Donohue PK, Northington FJ. Increased
morbidity in severe early intrauterine growth restriction.
J Perinatol 2004;24:735-8.
12. Schiff E, Friedman SA, Mercer BM, Sibai BM. Fetal lung
maturity is not accelerated in preeclamptic pregnancies.
Am J Obstet Gynecol 1993;1069:1096-101.
Published
2021-08-10
Section
Articles