Evaluation of Hemodynamic Response in Patients Undergoing Laparoscopic Surgeries Premedicated with Oral Clonidine
Background: Although laparoscopic surgeries have revolutionized the surgical field due to limited incisions, it has several
disadvantages such as creation of pneumoperitoneum for the surgical procedure can have several adverse hemodynamic and
respiratory consequences. Hence efficacy of oral clonidine as premedication in attenuation of such hemodynamic changes.
Materials and Methods: Forty patients needed for laparoscopy and 40 controlled (placebo) were studied. Their heart rate (HR)
and blood pressure were studied and compared in both groups.
Results: HR and blood pressure just after intubation, 5 min after intubation, 5 min after insufflations, 15 min after insufflations,
and 30 min after insufflations. After extubation was compared in both groups and there were significant results P < 0.001.
Conclusion: Oral clonidine effectively attenuates the hemodynamic responses to pneumoperitoneum and also provides sedation
without respiratory distress. Oral clonidine drug has proved ideal anesthetic agent for laparoscopic surgery.
Maze M, Tranquilli W. Alpha-2 adrenoceptor agonists:
Thotaand and Chowdary: Hemodynamic Response in Patients Undergoing Laparoscopic Surgeries Premedicated with Oral Clonidine
IJSS Journal of Surgery | Nov-Dec 2021 | Volume 7 | Issue 6 17
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